Arthritis can mean joint inflammation, one of the diseases which include around 200 rheumatic diseases and conditions that affect joints and other connective tissues.
Most commonly the people suffer from osteoarthritis and rheumatic conditions related to arthritis such as fibromyalgia, gout and rheumatoid arthritis.
Lupus and rheumatoid arthritis affect various body organs and cause lots of symptoms. Arthritis can impair a person’s ability to perform normal or everyday tasks and impair physical activity. It can cause pain, inflammation, swelling, stiffness of joints and muscles.
The symptoms can develop gradually or suddenly. Certain conditions can involve the immune system and various organs of the body. Some forms of arthritis can affect multiple organs and cause different unpleasant symptoms.
Treatment for arthritis is directed to control pain, minimize joint damage and improve and maintain quality of life. The therapy may include a combination of medications, physical therapies and patient education and support.
There are lots of musculoskeletal conditions which can be put into different groups: inflammatory arthritis, degenerative arthritis, soft tissue musculoskeletal pain, back pain, infectious arthritis, metabolic arthritis, connective tissue arthritis.
The widespread or located pain, abnormal pain processing, sleep disturbance, fatigue and psychological distress can make life unbearable for people with arthritis condition.
Different types of arthritis can vary widely, the location of symptoms of arthritis can also vary. The symptoms depend on the type of the condition.
Arthritis is in most cases a chronic disease with the symptoms occurring and persisting over time.
The symptoms and signs of arthritis should be discussed with a doctor. Constant pain from arthritis isolated to one place or felt in many parts of the body should be relieved with the modern and effective treatment methods.
The medications for arthritis can also help reduce swelling, stiffness and moving problems.
Non-inflammatory types of arthritis such as osteoarthritis are often treated with pain-relieving medications, physical exercises, and body weight reduction.
Celebrex medication is often used for non-inflammatory types of arthritis as well as for inflammatory types. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs). It is an analgesic reducing pain with effect of reduction of the inflammation.
Celebrex is available as tablets used orally as prescribed. This medicine can decrease pain signals from the joint and lessen pain. Besides, the medicine reduces inflammation and thus improves flexibility of the tissues, joints and muscles.
Before using Celebrex it is absolutely necessary to visit a doctor. The conditions for which Celebrex can be applied are various, still some patients may have special dosage adjustments or limitations of use.
The doctor should be in the know about all other health diseases and conditions a patient has or has previously suffered from. It is important to pay attention to other anti-inflammatory agents and other medicines you use before applying Celebrex. This medicine can interact with certain other medicines and medical products.
The treatment with Celebrex can improve the general health condition but should be as long as the doctor recommends.
Caring for aging people is always a great responsibility and hard work. Sometimes it is absolutely necessary to move an old person to a nursing home to provide the required safety and guardianship which you cannot give at home.
Plenty of successful attempts are carried out by special organizations to ensure the proper care and safekeeping of aging people who cannot stay at home due to serious disorders like stroke or pneumonia, paralyzed body organs, dementia and Alzheimer’s disease.
Under good caring conditions, patients of such homes live longer and healthier lives. Very often nursing homes look like usual homes and/or try to transform existing facilities into places that look like them. Recuperation is the most expected outcome for patients who need everyday care and medical assistance. The efficiency, with which caring homes serves their residents, should be estimated and controlled by particular authoritative organs.
Arranged for home-care aides, nursing homes care for their aging patients. Today traditional models of nursing homes have changed to totally different ones with innovative approaches for people with various debilitating diseases such as ALS (Amyotrophic Lateral Sclerosis) and MS (Multiple Sclerosis).
Such projects today represent the other vision of care for elderly people. They are not hospitals, but homes for sick or disabled allowing more choices of living their lives.
The facilities of modern nursing homes meet the government regulations and even have qualifications for payments from the authorities (in the countries where it is possible). The staff of modern nursing homes is devoted their work and help elderly people feel at home, needed and loved.
A great number of old people experience difficulty performing one or two activities of daily living. This may include bathing, dressing, eating, walking, transferring out of a bed or chair, and using the toilet. For such people long-term care is the best way to have 24 –hour care and medical assistance additionally to communication and companionship with other inhabitants of caring homes.
The assisted living is considered substantial for those who get sick or have some limitations of movements. As nursing homes provide elderly with round-the-clock care and happiness of enjoying friendship, they often represent places where people feel healthy, comfortable and cheerful.
By choosing a proper caring home, you make the right decision for your relatives who need support. Selecting a family-oriented, friendly environment pay attention to the other aspects which your relative or parent may need.
It is not hard to enhance and enrich the lives of the elderly. Modern facility nursing homes grant with cozy, comfortable places all their residents and provide a space where they are cared for with love, compassion and respect.
Best caring homes offer comprehensive services designed to meet individual needs and personalized patronage.
Extensive array of services for all residents and friendly staff usually make staying in nursing homes wonderful experiences.
Some medicines must not be used for a long period of time. They may bring not only the needed effects, but harm general health of a person. Try to use the medicine you have been prescribed as long as recommended and in the dose adjusted individually for you.
Celebrex belongs to non-steroidal drugs with high potential to reduce inflammation and pain. It is commonly prescribed to treat arthritis, acute pain, and menstrual aches and discomforts.
Before using this drug a person should make sure it is safe for him/her. The medicine blocks the enzyme that produces prostaglandins and thus reduces pain and swelling. Ask your doctor if it is suitable for you.
Regular use of this medicine is not recommended. It should be used only in the period of acute form of condition causing pain and inflammation.
Certain groups of patients need special dose adjustments and monitoring of body organs when they are suggested to use Celebrex.
Hepatic impairment (insufficiency): patients with liver problem should receive no more than half of the normal Celebrex dose. Patients with severe hepatic problem should not use Celebrex at all.
Patients with problem of swallowing of capsules: patients who cannot swallow capsules can use the content of the capsule with water or other liquid.
Patients with a metabolism problem (poorly metabolize CYP2C9 substrates) due to genotype or previous history of inadequate reactions to CYP2C9 substrates: should receive the half of the lowest Celebrex dose.
Patients with hypersensitivity to NSAIDs: such patients should not use Celebrex. Such patients may experience increased response to Celbrex treatment and need other options.
Patients with gastrointestinal bleeding: such patients should not use Celebrex.
Celebrex mode of action
The actual mechanism of Celebrex action is not clearly understood. The medicine produces pronounced anti-inflammatory effects with analgesia. These effects are supposed to be linked to the drug’s potential to inhibit prostaglandins (naturally occurring fatty acids which regulate inflammatory mediation).
The medicine also produces antipyretic effect (lowering temperature and fever) and pain reduction. Celecoxib selectively inhibits cyclooxygenase-2 (COX-2)isoenzyme. Researches suggest that the analgesic effects of Celecoxib are mediated by the blockade of COX – 2 enzyme. The medicine does not block COX-1 enzyme and thus does not cause any gastroenterological ill-effects involved in traditional NSAIDs treatment.
When the drug choice is in question several factors are taken into consideration. It is always recommended to start with mild analgesics at the lowest effective dose.
Celebrex is available in the form of capsules containing either of 50 mg, 100 mg, 200 mg and 400 mg of celecoxib.
As the medicine may cause serious heart and blood circulation effects if used for a long time, its use should be controlled and its dose should not exceed the lowest effective one.
For the treatment of osteoarthritis and rheumatoid arthritis it is recommended to use 200 mg of Celebrex once a day or in divided doses.
For the healing of juvenile rheumatoid arthritis and pain relief in children the dose of Celebrex is chosen in accordance with a body weight of a patient. Children whose body weight is from 10 kg to 25 kg should receive 50 mg of Celebrex two times a day. Children who weigh more than 25 mg can receive 100 mg two times a day.
For the treatment of ankylosing spondylitis, the dose of 200 mg is most effective. The dose should be used once a day or in divided doses two times a day. Patients with ankylosing spondylitis may need larger doses up to 400 mg per day to relief the symptoms of this condition.
In the treatment of dysmenorrhea and for pain relief the dose of 400 mg as initial is usually effective. In the following days of treatment the dose of 200 mg should be used.
Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug indicated to reduce pain and inflammation in the body. The hormones causing discomfort, pain and swelling are inhibited by celecoxib. The medicine is available in the capsules containing 50 mg, 100 mg, 200 mg or 400 mg of celecoxib.
Celebrex is effective in the treatment of pain or inflammation caused by arthritis, ankylosing spondylitis, hereditary polyps in the colon and menstrual pain.
For the relief of pain and other symptoms of the following conditions, Celebrex is prescribed in the lowest effective dose:
• Rheumatoid Arthritis
• Juvenile Rheumatoid Arthritis
• Ankylosing Spondylitis
• Acute Pain
• Primary Dysmenorrhea
Before using Celebrex a person should get assured that the medicine is safe for health.